New infections and HIV-1 subtypes among febrile persons and blood donors in Oyo State, Nigeria.

ABSTRACT:

Purpose

There were approximately 37.9 million persons infected with HIV in 2018 globally, resulting in 770,000 deaths annually. Over 50% of this infection and deaths occur in sub-Saharan Africa, with countries like Nigeria being seriously affected. Nigeria has one of the highest rates of new infections globally. To control HIV infection in Nigeria, there is a need to continually screen high-risk groups for early HIV infection and subtypes using very sensitive methods. In this study, new HIV-1 infection and circulating HIV-1 subtypes among febrile persons and blood donors were determined. Performance characteristics of three commercial EIA kits were also evaluated.

Methods

In total, 1028 participants were recruited for the study. New HIV-1 infection and subtypes were determin

SUBMITTER: Olusola BA 

PROVIDER: S-EPMC8238807 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature