Amygdala Functional Connectivity and Negative Reactive Temperament at Age 4 Months.

ABSTRACT:

Objective

Infant amygdala connectivity correlates with maternal reports of infant temperament characterized by novelty-evoked distress and avoidance. However, no studies have examined how human infant amygdala connectivity relates to direct observations of novelty-evoked distress. This study examined the link between amygdala connectivity and infant novelty-evoked distress using direct observation of temperament.

Method

Novelty-evoked distress was assessed at 4 months of age (N = 90) using a standardized reactivity assessment and parent report. Within 3 weeks of assessment, resting-state functional magnetic resonance imaging was collected in a subset of infants (n = 34). Using a whole-brain voxelwise approach, amygdala connectivity associated with positive and negative affec

SUBMITTER: Filippi CA 

PROVIDER: S-EPMC8239057 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature