Predictors of fatal outcomes among hospitalized COVID-19 patients with pre-existing hypertension in China.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) is an emerging, rapidly evolving pandemic, hypertension is one of the most common co-existing chronic conditions and a risk factor for mortality. Nearly one-third of the adult population is hypertensive worldwide, it is urgent to identify the factors that determine the clinical course and outcomes of COVID-19 patients with hypertension.

Methods and results

148 COVID-19 patients with pre-existing hypertension with clarified outcomes (discharge or deceased) from a national cohort in China were included in this study, of whom 103 were discharged and 45 died in hospital. Multivariate regression showed higher odds of in-hospital death associated with high-sensitivity cardiac troponin (hs-cTn) > 28 pg/ml (hazard ratio [HR]: 3.27, 95%

SUBMITTER: Wang T 

PROVIDER: S-EPMC8239823 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature