COVID-19 infection in CVID patients: What we know so far.

ABSTRACT:

Introduction

In patients with common variable immunodeficiency (CVID), immunological response is compromised. Knowledge about COVID-19 in CVID patients is sparse. We, here, synthesize current research addressing the level of threat COVID-19 poses to CVID patients and the best-known treatments.

Method

Review of 14 publications.

Results

The number of CVID patients with moderate to severe (~29%) and critical infection courses (~10%), and the number of fatal cases (~13%), are increased compared to the general picture of COVID-19 infection. However, this might be an overestimate. Systematic cohort-wide studies are lacking, and asymptomatic or mild cases among CVID patients occur that can easily remain unnoticed. Regular immunoglobulin replacement therapy was administered i

SUBMITTER: Weifenbach N 

PROVIDER: S-EPMC8239877 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature