Stool pattern is associated with not only the prevalence of tumorigenic bacteria isolated from fecal matter but also plasma and fecal fatty acids in healthy Japanese adults.

ABSTRACT:

Background

Colibactin-producing Escherichia coli containing polyketide synthase (pks⁺ E. coli) has been shown to be involved in colorectal cancer (CRC) development through gut microbiota analysis in animal models. Stool status has been associated with potentially adverse gut microbiome profiles from fecal analysis in adults. We examined the association between stool patterns and the prevalence of pks⁺ E. coli isolated from microbiota in fecal samples of 224 healthy Japanese individuals.

Results

Stool patterns were determined through factorial analysis using a previously validated questionnaire that included stool frequency, volume, color, shape, and odor. Factor scores were classified into tertiles. The prevalence of pks⁺ E. coli was determin

SUBMITTER: Watanabe D 

PROVIDER: S-EPMC8240356 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature