Feasibility of controlling hepatitis E in Jiangsu Province, China: a modelling study.

ABSTRACT:

Background

Hepatitis E, an acute zoonotic disease caused by the hepatitis E virus (HEV), has a relatively high burden in developing countries. The current research model on hepatitis E mainly uses experimental animal models (such as pigs, chickens, and rabbits) to explain the transmission of HEV. Few studies have developed a multi-host and multi-route transmission dynamic model (MHMRTDM) to explore the transmission feature of HEV. Hence, this study aimed to explore its transmission and evaluate the effectiveness of intervention using the dataset of Jiangsu Province.

Methods

We developed a dataset comprising all reported HEV cases in Jiangsu Province from 2005 to 2018. The MHMRTDM was developed according to the natural history of HEV cases among humans and pigs and the multi-

SUBMITTER: Yang M 

PROVIDER: S-EPMC8240442 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature