Association of low birth weight with cardiometabolic diseases in Swedish twins: a population-based cohort study.

ABSTRACT:

Objectives

To examine the association between low birth weight (LBW) and cardiometabolic diseases (CMDs, including heart disease, stroke and type 2 diabetes mellitus) in adulthood, and to explore whether genetic, early-life environmental and healthy lifestyle factors play a role in this association.

Design

A population-based twin study.

Setting

Twins from the Swedish Twin Registry who were born in 1958 or earlier participated in the Screening Across the Lifespan Twin (SALT) study for a full-scale screening during 1998-2002 and were followed up until 2014.

Participants

19 779 twin individuals in Sweden with birthweight data available (mean age: 55.45 years).

Primary and secondary outcome measures

CMDs were assessed based on self-reported medical records,

SUBMITTER: Li X 

PROVIDER: S-EPMC8240562 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature