Efficacy and safety of hyperbaric oxygen therapy for moderate-to-severe ulcerative colitis: a protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

Ulcerative colitis (UC) is a type of inflammatory bowel disease, and 62% of patients with UC felt that it is difficult for them to live a normal life. Furthermore, some researches have shown that about 15% of patients with UC undergo at least one extreme clinical course in their lifetime, and 10%-30% of patients with UC oblige colectomy. Although many investigations have demonstrated that HBO₂ has a beneficial impact on UC treatment, a systematic review and meta-analysis are unavailable. Therefore, a meta-analysis is essential to assess the efficacy and safety of HBO₂ in treating UC.

Methods and analysis

A systematic search plan will be performed in the following seven databases with a restriction of time from inception to September 2020 to

SUBMITTER: Luo L 

PROVIDER: S-EPMC8240565 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature