Relationships Between Sensorimotor Inhibition and Mobility in Older Adults With and Without Parkinson's Disease.

ABSTRACT:

Background

Reduced cortical sensorimotor inhibition is associated with mobility and cognitive impairments in people with Parkinson's disease (PD) and older adults (OAs). However, there is a lack of clarity regarding the relationships among sensorimotor, cognitive, and mobility impairments. The purpose of this study was to determine how cortical sensorimotor inhibition relates to impairments in mobility and cognition in people with PD and OAs.

Method

Cortical sensorimotor inhibition was characterized with short-latency afferent inhibition (SAI) in 81 people with PD and 69 OAs. Six inertial sensors recorded single- and dual-task gait and postural sway characteristics during a 2-minute walk and a 1-minute quiet stance. Cognition was assessed across the memory, visuospatial, exe

SUBMITTER: Martini DN 

PROVIDER: S-EPMC8240993 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature