Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making.

ABSTRACT: More than 1.6 million Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) tests were administered daily in the United States at the peak of the epidemic, with a significant focus on individual treatment. Here, we show that objective-driven, strategic sampling designs and analyses can maximize information gain at the population level, which is necessary to increase situational awareness and predict, prepare for, and respond to a pandemic, while also continuing to inform individual treatment. By focusing on specific objectives such as individual treatment or disease prediction and control (e.g., via the collection of population-level statistics to inform lockdown measures or vaccine rollout) and drawing from the literature on capture-recapture methods to deal with nonrandom sampling

SUBMITTER: Nichols JD 

PROVIDER: S-EPMC8241114 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature