Optimizing preoperative antibiotics in patients with β-lactam allergies: A role for pharmacy.

ABSTRACT:

Purpose

Patients with a reported β-lactam allergy (BLA) are often given alternative perioperative antibiotic prophylaxis, increasing risk of surgical site infections (SSIs), acute kidney injury (AKI), and Clostridioides difficile infection (CDI). The purpose of this study was to implement and evaluate a pharmacist-led BLA clarification interview service in the preoperative setting.

Methods

A pharmacist performed BLA clarification telephone interviews before elective procedures from November 2018 to March 2019. On the basis of allergy history and a decision algorithm, first-line preoperative antibiotics, alternative antibiotics, or allergy testing referral was recommended. The pharmacist intervention (PI) group was compared to a standard of care (SOC) group who underwent surg

SUBMITTER: Kwiatkowski S 

PROVIDER: S-EPMC8241474 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature