Ontology highlight
ABSTRACT:
SUBMITTER: Alimohamadi H
PROVIDER: S-EPMC8242199 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Alimohamadi Haleh H Bell Miriam K MK Halpain Shelley S Rangamani Padmini P
Frontiers in physiology 20210616
Dendritic spines are small, bulbous protrusions along the dendrites of neurons and are sites of excitatory postsynaptic activity. The morphology of spines has been implicated in their function in synaptic plasticity and their shapes have been well-characterized, but the potential mechanics underlying their shape development and maintenance have not yet been fully understood. In this work, we explore the mechanical principles that could underlie specific shapes using a minimal biophysical model o ...[more]