Characterization of T lymphocytes in severe COVID-19 patients.

ABSTRACT: In this observational study, 13 patients with severe COVID-19 and 10 healthy controls were enrolled. The data concerning the analysis of circulating T cells show that, in severe COVID-19 patients, the expansion of these cell compartments is prone to induce antibody response, inflammation (CCR4+ and CCR6+ TFH) and regulation (CD8+ Treg). This pathogenic mechanism could lead us to envision a possible new form of biological target therapy.

SUBMITTER: Fenoglio D 

PROVIDER: S-EPMC8242373 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature