Vertical transmission of SARS-CoV2 during pregnancy: A high-risk cohort.

ABSTRACT:

Objective

Identify the potential for and risk factors of SARS-CoV-2 vertical transmission.

Methods

Symptomatic pregnant women with COVID-19 diagnosis in whom PCR for SARS-CoV-2 was performed at delivery using maternal serum and at least one of the biological samples: cord blood (CB), amniotic fluid (AF), colostrum and/or oropharyngeal swab (OPS) of the neonate. The association of parameters with maternal, AF and/or CB positivity and the influence of SARS-CoV-2 positivity in AF and/or CB on neonatal outcomes were investigated.

Results

Overall 73.4% (80/109) were admitted in hospital due to COVID-19, 22.9% needed intensive care and there were four maternal deaths. Positive RT-PCR for SARS-CoV-2 was observed in 14.7% of maternal blood, 13.9% of AF, 6.7% of CB, 2.1% of co

SUBMITTER: Maeda MFY 

PROVIDER: S-EPMC8242902 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature