Taxonomic Characterization and Short-Chain Fatty Acids Production of the Obese Microbiota.

ABSTRACT: Intestinal microbiota seems to play a key role in obesity. The impact of the composition and/or functionality of the obesity-associated microbiota have yet to be fully characterized. This work assessed the significance of the taxonomic composition and/or metabolic activity of obese- microbiota by massive 16S rRNA gene sequencing of the fecal microbiome of obese and normoweight individuals. The obese metabolic activity was also assessed by in vitro incubation of obese and normoweight microbiotas in nutritive mediums with different energy content. We found that the microbiome richness and diversity of the two groups did not differ significantly, except for Chao1 index, significantly higher in normoweight individuals. At phylum level, neither the abundance of Firmicutes or Ba

SUBMITTER: Martinez-Cuesta MC 

PROVIDER: S-EPMC8242951 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature