Viral transmission and evolution dynamics of SARS-CoV-2 in shipboard quarantine.

ABSTRACT:

Objective

To examine transmission and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in shipboard quarantine of the Diamond Princess cruise ship.

Methods

We obtained the full SARS-CoV-2 genome sequences of 28 samples from the Global Initiative on Sharing All Influenza Data database. The samples were collected between 10 and 25 February 2020 and came for individuals who had been tested for SARS-CoV-2 during the quarantine on the cruise ship. These samples were later sequenced in either Japan or the United States of America. We analysed evolution dynamics of SARS-CoV-2 using computational tools of phylogenetics, natural selection pressure and genetic linkage.

Findings

The SARS-CoV-2 outbreak in the cruise most likely originated from either a s

SUBMITTER: Yeh TY 

PROVIDER: S-EPMC8243027 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature