Burden, treatment use, and outcome of secondary mitral regurgitation across the spectrum of heart failure: observational cohort study.

ABSTRACT:

Objectives

To define prevalence, long term outcome, and treatment standards of secondary mitral regurgitation (sMR) across the heart failure spectrum.

Design

Large scale cohort study.

Setting

Observational cohort study with data from the Viennese community healthcare provider network between 2010 and 2020, Austria.

Participants

13 223 patients with sMR across all heart failure subtypes.

Main outcome measures

Association between sMR and mortality in patients assigned by guideline diagnostic criteria to one of three heart failure subtypes: reduced, mid-range, and preserved ejection fraction, was assessed.

Results

Severe sMR was diagnosed in 1317 patients (10%), correlated with increasing age (P<0.001), occurred across the entire spectrum of heart fa

SUBMITTER: Bartko PE 

PROVIDER: S-EPMC8243241 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature