Relationship Between Depression/Anxiety and Cognitive Function Before and 6 Weeks After Major Non-Cardiac Surgery in Older Adults.

ABSTRACT:

Objective

To determine the relationship between affective measures and cognition before and after non-cardiac surgery in older adults.

Methods

Observational prospective cohort study in 103 surgical patients age ≥ 60 years old. All participants underwent cognitive testing, Center for Epidemiologic Studies-Depression, and State Anxiety Inventory screening before and 6 weeks after surgery. Cognitive test scores were combined by factor analysis into 4 cognitive domains, whose mean was defined as the continuous cognitive index (CCI). Postoperative global cognitive change was defined by CCI change from before to after surgery, with negative CCI change indicating worsened postoperative global cognition and vice versa.

Results

Lower global cognition before surgery was

SUBMITTER: Oyeyemi DM 

PROVIDER: S-EPMC8243391 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature