Fasted and fed small bowel motility patterns at cine-MRI in chronic intestinal pseudo-obstruction.

ABSTRACT:

Background

Chronic intestinal pseudo-obstruction (CIPO) is a severe intestinal motility disorder of which the pathophysiology is largely unknown. This study aimed at gaining insight in fasted and fed small bowel motility in CIPO patients using cine-MRI with caloric stimulation.

Methods

Eight adult patients with manometrically confirmed CIPO were prospectively included. Patients underwent a cine-MRI protocol after an overnight fast, comprising fasting-state scans and scans after ingestion of a meal (Nutridrink, 300 kcal). Small bowel motility was quantified resulting in a motility score in arbitrary units (AU) and visually assessed by three radiologists. Findings were compared with those in 16 healthy volunteers.

Key results

Motility scores (median, IQR) in CIPO patien

SUBMITTER: van Rijn KL 

PROVIDER: S-EPMC8244096 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature