Time to blastulation is superior to individual components of embryo grading for live-birth prediction.

ABSTRACT:

Objective

To compare components of the embryo grading system with time for blastocyst formation (i.e., day of embryo transfer) for predicting live-birth rate in frozen embryo transfer cycles.

Design

Retrospective cohort study.

Setting

University-affiliated fertility clinic.

Patients

From January 2015 to October 2018, 870 frozen embryos transferred in a total of 509 women and 728 cycles at our institution.

Interventions

None.

Main outcome measures

Probability of live birth per cycle.

Results

In unadjusted analysis of embryo grading components, both inner cell mass (ICM) and trophectoderm grades demonstrated a correlation with live-birth rates. However, this effect was lost in the ICM subgroup analysis by day of embryo transfer and preserved

SUBMITTER: Moustafa SM 

PROVIDER: S-EPMC8244320 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature