Embryos from polycystic ovary syndrome patients with hyperandrogenemia reach morula stage faster than controls.

ABSTRACT:

Objective

To investigate if patients with polycystic ovary syndrome (PCOS) have altered embryo morphokinetics when compared with controls.

Design

Retrospective cohort analysis.

Setting

Single academic fertility clinic in a tertiary hospital setting.

Patients

Age- and body mass index-matched patients who underwent in vitro fertilization diagnosed with PCOS using the Rotterdam criteria. A subanalysis was performed on patients with PCOS with hyperandrogenemia. Sixty-four patients with PCOS were identified with 990 embryos that were matched with 64 control patients with 628 embryos.

Interventions

None.

Main outcome measures

Time to blastulation.

Results

Embryos from women with PCOS displayed faster growth rate at t7, t8, and t9; all other morph

SUBMITTER: Chappell NR 

PROVIDER: S-EPMC8244380 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature