A Population-Based Study of Pre-Existing Health Conditions in Traumatic Brain Injury.

ABSTRACT: Health factors impacting both the occurrence of, and recovery from traumatic brain injury (TBI) vary in complexity, and present genuine challenges to researchers and healthcare professionals seeking to characterize injury consequences and determine prognosis. However, attempts to clarify causal links between injury characteristics and clinical outcomes (including mortality) often compel researchers to exclude pre-existing health conditions (PECs) in their samples, including psychiatric history, medication usage, and other comorbid conditions. In this pre-registered population-based study (total starting n = 939,123 patients), we examined trends in PEC incidence over 22 years in the state of Pennsylvania (1997-2019) in individuals sustaining TBI (n = 169,452) and individuals w

SUBMITTER: Dell KC 

PROVIDER: S-EPMC8244518 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature