Clathrin Is Important for Virulence Factors Delivery in the Necrotrophic Fungus Botrytis cinerea.

ABSTRACT: Fungi are the most prevalent plant pathogens, causing annually important damages. To infect and colonize their hosts, they secrete effectors including hydrolytic enzymes able to kill and macerate plant tissues. These secreted proteins are transported from the Endoplasmic Reticulum and the Golgi apparatus to the extracellular space through intracellular vesicles. In pathogenic fungi, intracellular vesicles were described but their biogenesis and their role in virulence remain unclear. In this study, we report the essential role of clathrin heavy chain (CHC) in the pathogenicity of Botrytis cinerea, the agent of gray mold disease. To investigate the importance of this protein involved in coat vesicles formation in eukaryotic cells, a T-DNA insertional mutant reduced in the expression

SUBMITTER: Souibgui E 

PROVIDER: S-EPMC8244658 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature