Clinical signs of possible serious infection and associated mortality among young infants presenting at first-level health facilities.

ABSTRACT:

Background

The World Health Organization recommends inpatient hospital treatment of young infants up to two months old with any sign of possible serious infection. However, each sign may have a different risk of death. The current study aims to calculate the case fatality ratio for infants with individual or combined signs of possible serious infection, stratified by inpatient or outpatient treatment.

Methods

We analysed data from the African Neonatal Sepsis Trial conducted in five sites in the Democratic Republic of the Congo, Kenya and Nigeria. Trained study nurses classified sick infants as pneumonia (fast breathing in 7-59 days old), severe pneumonia (fast breathing in 0-6 days old), clinical severe infection [severe chest indrawing, high (> = 38°C) or low body temperatu

SUBMITTER: Nisar YB 

PROVIDER: S-EPMC8244884 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature