Presymptomatic transmission of SARS-CoV-2 infection: a secondary analysis using published data.

ABSTRACT:

Objective

To estimate the proportion of presymptomatic transmission of SARS-CoV-2 infection that can occur, and the timing of transmission relative to symptom onset.

Setting/design

Secondary analysis of international published data.

Data sources

Meta-analysis of COVID-19 incubation period and a rapid review of serial interval and generation time, which are published separately.

Participants

Data from China, the Islamic Republic of Iran, Italy, Republic of Korea, Singapore and Vietnam from December 2019 to May 2020.

Methods

Simulations were generated of incubation period and of serial interval or generation time. From these, transmission times relative to symptom onset, and the proportion of presymptomatic transmission, were estimated.

Outcome measures

SUBMITTER: Casey-Bryars M 

PROVIDER: S-EPMC8245290 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature