Cancer Aging Research Group (CARG) score in older adults undergoing curative intent chemotherapy: a prospective cohort study.

ABSTRACT:

Importance

The Cancer Aging Research Group (CARG) toxicity score is used to assess toxicity risk in geriatric patients receiving chemotherapy.

Objective

The primary aim was to validate the CARG score in geriatric patients treated with curative intent chemotherapy in predicting grade 3-5 toxicities.

Design

This was a longitudinal prospective observational study.

Setting

Tata Memorial Hospital, Mumbai, India, a tertiary cancer care referral centre.

Participants

Patients, aged ≥65 years, with gastrointestinal, breast or gynaecological stage I-III cancers being planned for curative intent chemotherapy. A total of 270 patients were required for accrual in the study.

Exposures

Total risk score ranged from 0 (lowest toxicity risk) to 19 (highest toxicity

SUBMITTER: Ostwal V 

PROVIDER: S-EPMC8245449 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature