Gestational Folate and Folic Acid Intake among Women in Canada at Higher Risk of Pre-Eclampsia.

ABSTRACT:

Background

Periconceptional folic acid (FA) supplementation is recommended to prevent neural tube defects; however, the extent to which recommendations are met through dietary sources and supplements is not clear.

Objectives

Our objective was to evaluate the dietary and supplemental intakes of FA in a Canadian pregnancy cohort and to determine the proportions of pregnant women exceeding the Estimated Average Requirement (EAR) and Tolerable Upper Intake Level (UL).

Methods

FACT (the Folic Acid Clinical Trial) was an international multicenter, randomized, double-blinded, placebo-controlled, phase III trial investigating FA for the prevention of pre-eclampsia in high-risk pregnancies. Participants were enrolled from Canadian sites at 8-16 weeks of gestation. Dietary and

SUBMITTER: Rose EG 

PROVIDER: S-EPMC8245867 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature