Developmental heatmaps of brain functional connectivity from newborns to 6-year-olds.

ABSTRACT: Different functional networks exhibit distinct longitudinal trajectories throughout development, but the timeline of the dynamics of functional connectivity across the whole brain remains to be elucidated. Here we used resting-state fMRI to investigate the development of voxel-level changes in functional connectivity across the first six years of life. Globally, we found that developmental changes in functional connectivity are nonlinear with more changes during the first postnatal year than the second, followed by most significant changes from ages 2-4 and from ages 4-6. However, the overall global difference observed between the first and second year appears to have been driven by girls. Limbic and subcortical areas consistently demonstrated the most substantial changes, whereas primary

SUBMITTER: Chen H 

PROVIDER: S-EPMC8246150 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature