An excellent nomogram predicts microvascular invasion that cannot independently stratify outcomes of small hepatocellular carcinoma.

ABSTRACT:

Background

Whether microvascular invasion is a prognosis factor for small hepatocellular carcinoma (sHCC) is controversial, and a preoperatively predictive model based on gadoxetate disodium (Gd-EOB-DTPA) MRI is clinically needed for MVI in sHCC.

Methods

Between March 2012 and September 2020, 455 consecutive patients with pathologically confirmed HCC ≤3 cm who underwent hepatectomy and preoperative Gd-EOB-DTPA MRI were retrospectively enrolled. Univariate and multivariate logistic regression combined with cox regression were conducted to find the confounding factors in the cohorts. Propensity score matching (PSM) was employed to balance the biases between MVI and non-MVI groups. Nomogram with C-index visualized the predictive model of MVI.

Results

Multivariate logisti

SUBMITTER: Chong H 

PROVIDER: S-EPMC8246205 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature