Modeling Cervical Cancer Screening Strategies With Varying Levels of Human Papillomavirus Vaccination.

ABSTRACT:

Importance

Cervical cancer screening is a lifesaving intervention, with an array of approaches, including liquid-based cytology (LBC), molecular testing for human papillomavirus (HPV) infection, and combinations via parallel cotesting or sequential triage. Maximizing screening efficacy while minimizing overtreatment is vital, especially when considering how the HPV vaccine will affect the interpretation of results.

Objectives

To estimate the likely outcomes of different screening modalities and to model how the increasing uptake of the HPV vaccine could affect the interpretation of screening results.

Design, setting, and participants

This decision analytic model established a simple Markov model to compare the outcomes of different cervical cancer screening modalities

SUBMITTER: Grimes DR 

PROVIDER: S-EPMC8246311 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature