Dairy consumption, plasma metabolites, and risk of type 2 diabetes.

ABSTRACT:

Background

Epidemiologic studies have reported a modest inverse association between dairy consumption and the risk of type 2 diabetes (T2D). Whether plasma metabolite profiles associated with dairy consumption reflect this relationship remains unknown.

Objectives

We aimed to identify the plasma metabolites associated with total and specific dairy consumption, and to evaluate the association between the identified multi-metabolite profiles and T2D.

Methods

The discovery population included 1833 participants from the Prevención con Dieta Mediterránea (PREDIMED) trial. The confirmatory cohorts included 1522 PREDIMED participants at year 1 of the trial and 4932 participants from the Nurses' Health Studies (NHS), Nurses' Health Study II (NHSII), and Health Professionals Fo

SUBMITTER: Drouin-Chartier JP 

PROVIDER: S-EPMC8246603 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature