Frequency of peripheral diseases in Korean patients with ankylosing spondylitis and the effectiveness of adalimumab.

ABSTRACT:

Aim

Peripheral features contribute to disease burden in ankylosing spondylitis (AS). This study investigated the frequency of peripheral disease and effectiveness of adalimumab among Korean patients with AS.

Methods

Peripheral disease was evaluated in consecutively enrolled patients with active AS (Bath Ankylosing Spondylitis Disease Activity Index [BASDAI] score ≥ 4). An adult subpopulation was subsequently enrolled in a prospective, observational study and received adalimumab 40 mg, every 2 weeks. During a 52-week follow-up, AS disease activity was assessed by BASDAI score, and effectiveness in peripheral disease assessed via changes in Maastricht Ankylosing Spondylitis Enthesitis Score (MASES; 0-13), swollen joint and tender joint counts (SJC, 0-44; TJC, 0-46), and dactyl

SUBMITTER: Lee SH 

PROVIDER: S-EPMC8246777 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature