Association Between Opioid Agonist Therapy and Testing, Treatment Uptake, and Treatment Outcomes for Hepatitis C Infection Among People Who Inject Drugs: A Systematic Review and Meta-analysis.

ABSTRACT:

Background

People who inject drugs (PWID) experience barriers to accessing testing and treatment for hepatitis C virus (HCV) infection. Opioid agonist therapy (OAT) may provide an opportunity to improve access to HCV care. This systematic review assessed the association of OAT and HCV testing, treatment, and treatment outcomes among PWID.

Methods

Bibliographic databases and conference presentations were searched for studies that assessed the association between OAT and HCV testing, treatment, and treatment outcomes (direct-acting antiviral [DAA] therapy only) among PWID (in the past year). Meta-analysis was used to pool estimates.

Results

Of 9877 articles identified, 22 studies conducted in Australia, Europe, North America, and Thailand were eligible and included. Ris

SUBMITTER: Grebely J 

PROVIDER: S-EPMC8246796 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature