Trends in the Incidence of Young-Onset Colorectal Cancer With a Focus on Years Approaching Screening Age: A Population-Based Longitudinal Study.

ABSTRACT:

Background

With recent evidence for the increasing risk of young-onset colorectal cancer (yCRC), we had the objective to evaluate the incidence of yCRC in 1-year age increments, particularly focusing around the screening age of 50 years.

Methods

We conducted a longitudinal study using linked administrative health databases in British Columbia, Canada, including a provincial cancer registry, inpatient and outpatient visits, and vital statistics from January 1, 1986, to December 31, 2016. We calculated incidence rates per 100 000 at every age from 20 to 60 years and estimated annual percent change in incidence (APCi) of yCRC using joinpoint regression analysis.

Results

We identified 3614 individuals with yCRC (49.9% women). The incidence of CRC steadily increased from 2

SUBMITTER: Howren A 

PROVIDER: S-EPMC8246802 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature