One-year outcomes of supersaturated oxygen therapy in acute anterior myocardial infarction: The IC-HOT study.

ABSTRACT:

Background

Supersaturated oxygen (SSO₂ ) has recently been approved by the U.S. Food and Drug Administration for administration after primary percutaneous coronary intervention (pPCI) in patients with anterior ST-segment elevation myocardial infarction (STEMI) based on its demonstration of infarct size reduction in the IC-HOT study.

Objectives

To describe the 1-year clinical outcomes of intracoronary SSO₂ treatment after pPCI in patients with anterior STEMI.

Methods

IC-HOT was a prospective, open-label, single-arm study in which 100 patients without cardiogenic shock undergoing successful pPCI of an occluded left anterior descending coronary artery were treated with a 60-min SSO₂ infusion. One-year clinical outcomes were compared with

SUBMITTER: Chen S 

PROVIDER: S-EPMC8246818 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature