Statin therapy and postoperative short-term mortality after rectal cancer surgery.

ABSTRACT:

Aim

This study aimed to assess the correlation between regular statin therapy and postoperative mortality following surgical resection for rectal cancer.

Method

This retrospective cohort study included all adult patients undergoing abdominal rectal cancer surgery in Sweden between January 2007 and September 2016. Data were gathered from the Swedish Colorectal Cancer Registry, a large population-based prospectively collected registry. Statin users were defined as patients with one or more collected prescriptions of a statin within 12 months before the date of surgery. The statin-positive and statin-negative cohorts were matched by propensity scores based on baseline demographics.

Results

A total of 11 966 patients underwent surgical resection for rectal cancer, of whom

SUBMITTER: Pourlotfi A 

PROVIDER: S-EPMC8246857 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature