Association between serum advanced oxidation protein products and mortality risk in maintenance hemodialysis patients.

ABSTRACT:

Background

The association between serum advanced oxidation protein products (AOPP) and mortality risk remains equivocal. We aimed to assess the correlation of serum AOPP levels with the risk of all-cause mortality in hemodialysis (HD) patients.

Methods

A total of 1394 maintenance HD patients with complete data on AOPP and related parameters were included from China Collaborative Study on Dialysis (CCSD), a multi-center, prospective cohort study. The primary outcome was all-cause mortality, the secondary outcome was cardiovascular disease (CVD) mortality.

Results

During a median follow-up duration of 5.2 years (IQR, 2.1-5.4), all-cause mortality occurred in 492 (31.4%) participants. Overall, there was a reversed L-shaped association between serum AOPP and all-cause mo

SUBMITTER: Zhou C 

PROVIDER: S-EPMC8247246 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature