A metabolic model of Lipomyces starkeyi for predicting lipogenesis potential from diverse low-cost substrates.

ABSTRACT:

Background

Lipomyces starkeyi has been widely regarded as a promising oleaginous yeast with broad industrial application prospects because of its wide substrate spectrum, good adaption to fermentation inhibitors, excellent fatty acid composition for high-quality biodiesel, and negligible lipid remobilization. However, the currently low experimental lipid yield of L. starkeyi prohibits its commercial success. Metabolic model is extremely valuable to comprehend the complex biochemical processes and provide great guidance for strain modification to facilitate the lipid biosynthesis.

Results

A small-scale metabolic model of L. starkeyi NRRL Y-11557 was constructed based on the genome annotation information. The theoretical lipid yields of glucose, cellobiose, xylose, glycerol, a

SUBMITTER: Zhou W 

PROVIDER: S-EPMC8247262 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature