Using next-generation sequencing to detect oral microbiome change following periodontal interventions: A systematic review.

ABSTRACT:

Objectives

This systematic review was to evaluate the change of oral microbiome based on next-generation sequencing (NGS)-metagenomic analysis following periodontal interventions among systematically healthy subjects.

Materials and methods

A structured search strategy consisting of "metagenomics" and "oral diseases" was applied to PubMed, EMBASE, and Web of Science to identify effective papers. The included studies were original studies published in English, using metagenomic approach to analyze the effectiveness of periodontal intervention on oral microbiome among systematically healthy human subjects with periodontitis.

Results

A total of 12 papers were included in this review. Due to the heterogeneity of selected study, quantitative analysis was not performed. The

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC8247266 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature