Novel Intermittent Dosing Burst Paradigm in Spinal Cord Stimulation.

ABSTRACT:

Introduction

Intermittent dosing (ID), in which periods of stimulation-on are alternated with periods of stimulation-off, is generally employed using 30 sec ON and 90 sec OFF intervals with burst spinal cord stimulation (SCS). The goal of this study was to evaluate the feasibility of using extended stimulation-off periods in patients with chronic intractable pain.

Materials and methods

This prospective, multicenter, feasibility trial evaluated the clinical efficacy of the following ID stimulation-off times: 90, 120, 150, and 360 sec with burst waveform parameters. After a successful trial (≥50% pain relief) using ID stimulation, subjects were titrated with OFF times beginning with 360 sec. Pain, quality of life, disability, and pain catastrophizing were evaluated at one, thr

SUBMITTER: Deer TR 

PROVIDER: S-EPMC8247280 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature