Ontology highlight
ABSTRACT:
SUBMITTER: Farcet JB
PROVIDER: S-EPMC8247325 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Farcet Jean-Baptiste JB Kindermann Johanna J Karbiener Michael M Scheinecker Richard R Kostner Otto O Kreil Thomas R TR
Journal of medical virology 20201217 6
In the 1980s, virus inactivation steps were implemented into the manufacturing of biopharmaceuticals in response to earlier unforeseen virus transmissions. The most effective inactivation process for lipid-enveloped viruses is the treatment by a combination of detergents, often including Triton X-100 (TX-100). Based on recent environmental concerns, the use of TX-100 in Europe will be ultimately banned, which forces the pharmaceutical industry, among others, to switch to an environmentally frien ...[more]