A systematic review of economic evaluations of advanced therapy medicinal products.

ABSTRACT:

Aims

Advanced therapy medicinal products (ATMPs) represent a new category of medicinal products with a potential for transformative improvements in health outcomes but at exceptionally high prices. Routine adoption of ATMPs requires robust evidence of their cost-effectiveness.

Methods

A systematic literature review of economic evaluations of ATMPs, including gene therapies, somatic cell therapies and tissue-engineered products, was conducted. Literature was searched using MedLine, Embase, PubMed, Cochrane Register, the NHS Economic Evaluation Database and the grey literature of health technology assessment organisations with search terms relating to ATMPs and economic evaluations. Titles were screened independently by 2 reviewers. Articles deemed to meet the inclusion criter

SUBMITTER: Lloyd-Williams H 

PROVIDER: S-EPMC8247439 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature