Donor to recipient ratios in the surgical treatment of vitiligo and piebaldism: a systematic review.

ABSTRACT: Stabilized vitiligo resistant to conventional therapy (e.g. segmental vitiligo) and piebaldism lesions can be treated with autologous cellular grafting techniques, such as non-cultured cell suspension transplantation (NCST) and cultured melanocyte transplantation (CMT). These methods are preferred when treating larger surface areas due to the small amount of donor skin needed. However, the donor to recipient expansion ratios and outcomes reported in studies with cellular grafting vary widely, and to date, no overview or guideline exists on the optimal ratio. The aim of our study was to obtain an overview of the various expansion ratios used in cellular grafting and to identify whether expansion ratios affect repigmentation and colour match. We performed a systematic literature search in ME

SUBMITTER: Narayan VS 

PROVIDER: S-EPMC8247963 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature