Prevalence of cognitive impairment and change in patients with breast cancer: A systematic review of longitudinal studies.

ABSTRACT:

Objective

Patients with breast cancer face cognitive impairment that affects their quality of life; partially attributable to treatment. Our aim was to detail the prevalence and change of cognitive impairment during the course of treatment. We also investigated the effect of therapy (chemotherapy [CT]) vs. radiotherapy and/or endocrine therapy vs. healthy controls).

Methods

This article reviews longitudinal cohort studies published to date in Medline and Embase that (i) assess cognition before and after therapy, (ii) report prevalence cognitive impairment or change, and (iii) use standardized and valid neuropsychological tests. We used the original authors' criteria for cognitive impairment.

Results

The title and abstract of 891 articles were screened, resulting in th

SUBMITTER: Dijkshoorn ABC 

PROVIDER: S-EPMC8248098 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature