Long-term follow-up of oxaliplatin-induced liver damage in patients with colorectal cancer.

ABSTRACT:

Objectives

To report the long-term follow-up data including computed tomography (CT) findings of oxaliplatin-induced liver damage in patients with colorectal cancer.

Methods

Three hundred and fifty-six patients who underwent surgery followed by oxaliplatin-based chemotherapy (OBC) for colorectal cancer between January 2013 and December 2014 were included. Abdominal CT images and laboratory results (serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), albumin, total bilirubin, and platelet counts) were reviewed immediately before (as baseline), during, and after adjuvant OBC. Abdominal CT images were reviewed to assess the heterogeneous liver parenchyma, increase in size of the spleen, development of acute portosystemic shunts during OBC, and imaging findin

SUBMITTER: Cha DI 

PROVIDER: S-EPMC8248204 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature