A new needle-based confocal laser endomicroscopy pattern of malignant pancreatic mucinous cystic lesions (with video).

ABSTRACT:

Background and objectives

The diagnosis of malignant pancreatic cystic lesions (PCLs) remains challenging. Needle-based confocal laser endomicroscopy (nCLE) is an emerging promising imaging technique capable of real-time in vivo microscopic imaging of the cyst wall. We aimed to develop and validate a new nCLE diagnostic criteria for malignant mucinous cystic lesions (MLs).

Methods

Patients referred for EUS-FNA of indeterminate PCLs with at least one worrisome features according to Fukouka consensus were consecutively prospectively enrolled from July 2016 to July 2018. The final diagnosis was based on surgical histology, cytopathology, or committee consensus. Five investigators nonblindly reviewed nCLE features and identified potential diagnostic feature for malignant MLs, wh

SUBMITTER: Feng Y 

PROVIDER: S-EPMC8248307 | biostudies-literature | 2021 May-Jun

REPOSITORIES: biostudies-literature