Predicting sample success for large-scale ancient DNA studies on marine mammals.

ABSTRACT: In recent years, nonhuman ancient DNA studies have begun to focus on larger sample sizes and whole genomes, offering the potential to reveal exciting and hitherto unknown answers to ongoing biological and archaeological questions. However, one major limitation to such studies is the substantial financial and time investments still required during sample screening, due to uncertainty regarding successful sample selection. This study investigates the effect of a wide range of sample properties including latitude, sample age, skeletal element, collagen preservation, and context on endogenous content and DNA damage profiles for 317 ancient and historic pinniped samples collected from across the North Atlantic and surrounding regions. Using generalised linear and mixed-effect models, we found t

SUBMITTER: Keighley X 

PROVIDER: S-EPMC8248401 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature