Comparison of the Clinical Value of miRNAs and Conventional Biomarkers in AMI: A Systematic Review.

ABSTRACT: Background/Aims: This study aimed to compare the clinical value of the peak time point and area under the curve (AUC) of miRNAs and conventional biomarkers in acute myocardial infarction (AMI). Methods: A literature search was carried out in PubMed, Web of Science, Embase, and Cochrane systematically. Screening studies, extracting data, and assessing article quality were performed independently by two researchers. Also, the names of miRNAs in the included studies were standardized by the miRBase database. Results: A total of 40 studies, encompassing 6,960 participants, were included in this systematic review. The samples of circulating miRNAs were mainly from the plasma. The results of this systematic review displayed that miR-1-3p, miR-19b-3p, miR-22-5p, miR-122-5p, m

SUBMITTER: Wang B 

PROVIDER: S-EPMC8248539 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature