Bidirectional association between periodontal disease and diabetes mellitus: a systematic review and meta-analysis of cohort studies.

ABSTRACT: Periodontal disease has been reported to be associated with diabetes mellitus. However, the direction of the association and the influence of bias are not clear. Thus, the aim of this systematic review and meta-analysis was to summarize the existing evidence on the bidirectional prospective association between periodontal disease and diabetes mellitus by accounting for the risk of bias of the original studies. The literature search was conducted on the electronic data sources PubMed and Web of Science up to February 9th, 2021. We included observational studies, which investigated the prospective association between diabetes mellitus and periodontal disease or vice versa. The risk of bias of the primary studies was evaluated by applying the Quality in Prognosis Studies (QUIPS) tool. Random

SUBMITTER: Stohr J 

PROVIDER: S-EPMC8249442 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature