Reconciling estimates of global spread and infection fatality rates of COVID-19: An overview of systematic evaluations.

ABSTRACT:

Background

Estimates of community spread and infection fatality rate (IFR) of COVID-19 have varied across studies. Efforts to synthesize the evidence reach seemingly discrepant conclusions.

Methods

Systematic evaluations of seroprevalence studies that had no restrictions based on country and which estimated either total number of people infected and/or aggregate IFRs were identified. Information was extracted and compared on eligibility criteria, searches, amount of evidence included, corrections/adjustments of seroprevalence and death counts, quantitative syntheses and handling of heterogeneity, main estimates and global representativeness.

Results

Six systematic evaluations were eligible. Each combined data from 10 to 338 studies (9-50 countries), because of differe

SUBMITTER: Ioannidis JPA 

PROVIDER: S-EPMC8250317 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature